Explore Wikis Community Central. Register Don't have an account? American Museum of Natural History. View source. History Talk 0. Chocobo banner. Categories Locations Parasite Eve Locations. Detective Cathy gives up the dog and he sleeps with it deeply. He doesn't know this would be the last time he sees the dog So where is Aya? The police officers are searching the around areas of Central Park but no one sees her. But they meet a wandering guy who seems to be mysterious who tries to pass the off-limit area.
The police interview him. He introduces to be Kunihiko Maeda - a Japanese scientist. It seems he doesn't want to answer the police. And it's lucky to him when one of the asking guys is burnt by Eve somewhere. Maeda runs away at once. So this guy saved her. And then Daniel comes either. Here they hear Maeda's story about a similar incident in Japan. So you know that the Mitochondria is aroused when an African scientist tried to culture his wife's liver cells to keep her alive which was named "Eve".
But then there was a kidney transplant that Eve was spread into another body of a young girl who might be Maya - Aya's sister. Aya is the only one who isn't ignited by Eve's power. She doesn't want to fight. She feels hurt. She thinks that because she is the same kind of Eve. Then both Maeda and Daniel go out, leave her thinking alone in the room. Next morning, you take control of Aya. Check the room for 30 bullets. Then go out. Poor Maeda! He is sleeping in the open. Then Daniel turns back, too.
Now all of you have something to come to the Museum of Natural History again. But Daniel says you can prepare here for a while. I remind you to agree with him and search the place. The right is the Pharmacy. These items are random, I'm not sure but they are what I got. There is a telephone for you to save, too. After finishing, just head to the left to a Gun Shop.
The Gun Shop is destroyed either. The lock of the entrance is spoiled that it can't be opened. But don't worry, Daniel's shot will solve all of those. Then you can enter the shop. When you have finished everything here, tell Daniel and he would pick you and Maeda to the Museum. Maeda is such a talented guy.
When Klamp is away, he does all his best to see Klamp's research about how the Mitochondria cells can invade human body. But then Klamp comes back and of course he has to get rid of them.
But now it's not time for him to be angry. NYPD Station was destroyed by something. The characters just see a mess in their eyes. Daniel checks the place and so does Aya. Maeda would give you a Good Luck Charm useless thing and then you take control of Aya. Return to the main hallway. Such a mess!
Go to the Meeting Room, I'm sure that there are new items here. You would be welcomed by a spider. Be careful and don't let yourself trapped in web or your speed would be reduce. Get out of the Meeting Room and head to the Weapon Department. Sometimes you can meet Dog mans here. They are such strong and wise enemies. See my strategy at "Monster List". In the Weapon Storage, you will meet Wayne and Torres who is going to die After that, Wayne stays in this storage.
He gives you the M92F handgun - Torres's weapon. This is not only a good weapon but a bad weapon as well. You can combine it with your gun if you have tools. Then head to the last room where Sheeva and some dogs were caught. You would see the cages become a mess. Detective Cathy is unconscious. Talk to her and she will let you know what happens, giving you 6 bullets.
But then you would be attacked by two Dog Men. Return to the hallway and go to the Locker Room to get Medicine 3. When you intend to enter the office, a Super Rat will attack you.
This rat is faster and more dangerous than the ones in Carnegie Hall and it's yellow. Entering the office and talk to an unconscious officer here. He would tell you more about the accident and give you 30 bullets. You will know that something happens to Ben's dog - Sheeva and the child is chasing after the dangerous dog. You would see a scene showing Ben who is chasing after Sheeva. The dof now looks like a crazy animal In the hallway, go up the right stairs and you see Nix was beaten with a police officer.
Talk to him and he will give you some ammo. Then head to the left path. You are in the first fork road where Ben was here to find Sheeva. Go to the first room you see. Two Dog Men will attack you.
Kill them and get inside the left room to find Storage Key. There is a treasure chest in the bottom right containing a Medicine 3. Get out of the room. Ben is at another fork road Sheeva is lost and the child is being surrounded by two Super Rats Go to the left room. Then get back to the fork road and head to the north stairs.
Three spiders would attack you You are in the next fork road where Ben was in danger. But you see nothing here. Go to the first room in sight. You meet the Lab Tech who would heal your health and fill your HP.
I think you should do this because the battles here are rather tremendous. You can fight some Rats, but you don't find Ben. Talk to the lying police for the Locker Key, then head to the north double door. A police officer is being beaten by a huge Dog Man. You can have SG after killing this monster.
Equip this weapon or combine it with your gun. Talk to that wounded police for ammo. Do you see a hidden hole in the north of the police? Check and get into it. You can find a SV Vest. Then get back to the fork road and go to the right path. Don't go to the left path soon. Just head to the north room to fight some spiders.
Sometimes you can receive three Medicine 3 or two with a PE Medicine. When you have done this, you can go to the right path of the hall. Just go along to the front door and prepare for a boss fight.
Ben is calming Sheeva but all of those are just useless. The dog is affected by Mitochondria cells and it is going to transform. Douglas Baker tries to protect the child while Sheeva is transforming. What a terrible scene! This dog is slow but its hits are rather heavy. You can't avoid its earthquake and it makes you lose a big number of HP. Sheeva can attack by casting a huge laser. You can completely anticipate the laser's way and avoid it as soon as possible. Run around and shoot but don't touch it in this small battlefield.
Sheeva's attacks are pretty impressive : - Bite : Well, he can do this attack whenever he wants. And the damage caused by this is pretty big. He suddenly dashes into you quickly, then bites you. Try to move aside as quickly as you can. You see him gathering triangular flashes, then he suddenly casts a big laser which lasts pretty long, and he quickly moves it over the battlefield to make you get hit.
The damage is average. But the attack is easy to avoid once you have got some practices. It takes Sheeva a long moment to charge the triagular flashes, and that's the chance for you to prepare yourself. Then he will cast the laser soon at where you are standing. And you, be faster than him, by running to the opposite side as soon as possible.
As I said, Sheeva will move the laser around as long as it's lasting. Standing around that side also makes you get hit as usual. So now you know what you must do? Your best position before Sheeva shoots the laser is either left or right side. You may lose about HP because of this attack. You can see there are many circles spread when the earhquake is happenning. Well, if you can stand out of the biggest circle, you'll be safe.
But doing that is nearly impossible, as the circles may occupy even the corners of the battlefield, as Sheeva usually does it from the center. Well, check up your health babe! Sheeva sometimes will make scream out that shakes the screen. Don't worry, that means one of his head is lost. And you should prepare for a new adventure that takes place in another position, not here With the keys you collected in Day 3, you can unlock the last room of Weapon Storage corridor.
Here there are three treasure chests for you to get. There might be a new weapon either. Then return to the main hallway and go to the laboratory where the Lab Tech and Maeda are working together. Then Daniel would come to tell you that they have just known Eve's destination would be the Hospital in New York. Then he gives you 30 bullets and you go with Maeda. Now you can check the place more if you want. Get out of Police Station and choose the Hospital to go.
It seems no one is inside. Aya must explore this place before Eve can do anything. Maeda again gives you a useless charm. Then you enter the hospital. There's no one here.
You open the door beside the reception desk to grab a Tool. There is Save Point here either. The door at the north is locked and you can't open it now. Go to the left path to the elevator area. You would see Maya in the other side of the left locked door.
But you can't follow her. Choose either elevator and get on it. Eve wants to joke you again. She would make some trouble that the elevator takes you to the basement area. The electric power is off. Now you must go in a rather dark atmosphere.
The door behind you wouldn't be opened until you unlock it from other side. Go down the screen to a turn path. You can go to the first door beside in Aya's right to get some ammo and M79 Grenade Launcher.
Here you find the Fuse 1 and some slime monsters would welcome you. Then get out by another door. You are at another corridor and Maya appears in the other side of the north door.
This door can't be unlocked if there's no electric power supplied. Just continue to go south. Go to the nearest door you see. There are some treasure chests here. Open them to get plus pieces of armor.
Then run to upper right to another area. Check the chest beside the skeleton to have Medicine 3. Then check the drawer of the desk. You get Autopsy Key. Then go out by the nearest door. Finding the locked door beside the storage, you enter Autopsy Room and Aya would discard the key.
Here you open a treasure chest to get Tool and go to the next door. First, go to the north to grab Fuse 2. In the right path, you grab a treasure chest and Blue Card Key from a burning corpse. You would be welcomed eagerly here by monsters. Go to the deepest right path to the place where you saw Maya. Unlock that door by using the Blue Card Key to access the switch on the wall. You can touch the Power Room.
Here there is a chest that contain a special weapon but not powerful. You can get it if you like. Maya is here and she continues to play with you the old game. Now open the right door. Get through the glass slide door and find a spawn here. You would a chest with Medicine 2 here. Then go to the bottom right and find Fuse 3 on the floor.
At the corridor where you have met Maya, go to the north to reach the fuse box. First, you must turn off the power or Aya would be shocked by your carelessness, then connect the two wires into each other. Put the three fuses on it. Finally, you turn on. The power would be supplied successfully. Turn right to the next corridor with the two elevators. Then use one of them to get down 1st floor. Return to the main hall. Now the door at north is unlocked.
You can enter it soon After being attacked by some monsters, you will meet a nurse and a patient. Then you go to the right sickroom and fight another group of enemies. Then suddenly Aya's memory arouses.
She remembers this was the place where she and Maya got treat after the accident. But Maya couldn't be saved Talk to the nurse and she would give Green Card Key which is used to unlock the door beside the elevators where you first met Maya here. So get back to that place. Let Aya talk to the nurse here. Then use the card to open the door. In the north you can find a chest with Bullet Capacity Plus. You can be welcomed by a huge slime.
After that, find a handle in the bottom right and turn it to activate the elevators to other floors. You can find a chest with 30 bullets here. Back to the elevator and get on it to 13th floor. Your only door you can go is in the left. After fighting the spawn, you can check around the room to grab a Medicine 3 and G3A3 Rifle. But the door to other area is locked.
Okay, now you try to find a white freezer in the left side. Then let Aya push it aside. There is a hidden switch behind it. Push it the you can go through the door.
Grab some chests go to the north path. Then enter the right room. You will find some documents saying about Aya's accident that includes info about her dead mother - Mariko Brea. Check the chests here to grab Cure- M and bullets. Then I remind you to save here. Get down the next elevator you see. It would take you to the terrace. Here you are attacked by a giant spider Currently you mightn't have Haste spell, unless you have tried to gain once more level.
It'll be better to have it. If not, remember to bring at least two Cure-M. The most important thing is that you must avoid its casting web or you would be petrified.
But don't let it strike you, too. Use the weapon with furthest range because this guy is too large to shoot. I have died a lot of times in this battle. After that, the spider would take you to another position to continue the fight. Then its HP remains Just beat as I told you. Now it can cast three webs at the same time and it's better for you to run and fire at the same time.
These are details about the boss' attacks : - Spider Webs : Wow, the boss will suddenly blow a very large-ranged web to you. This attack is extremely annoying, because Spider Woman will turn you into a toy while you are petrified, and then enjoy your life! If you have got Haste spell, cast it on Aya and move aside to dodge the web easily.
If not, try running as fast as you can, to reduce the percentage of being caught. Then it suddenly casts a flame through you. This attack is hard to dodge like the Spider Webs. Although the flame flies to you slowly, its size is big enough to reach Aya while she is running. As usual, Haste is the easiest solution to avoid this. And if you don't have it, do the same as dodging the Spider Webs. Huh, let's imaginw when you are being stuck, the Spider Woman is very glad to shoot this.
So Spider Web is still your first attention. Hoo-hoo, stay away from the boss when it is coming to you okay? Getting aside is not the best idea now. Haste is your friend now!!! After the fight, the spider would be dropped down by a ground breaking and you receive EXP and G23 Handgun. The ambition of the largest liberation makes her insane. She would kill you now The airplanes of some soldiers are flying through this place.
She uses her deadly eyes to kill him that the plane loses control. Its engine has been destroyed after a crash and it is toward the hospital terrace. Eve has gone and now Aya must escape from the death coming. An explosion would happen soon. Try to control her to run to the bottom left of the terrace.
She would find an emergency elevator to get down at once and escape But then, a little spider would appear to fight you. Just kill it and Aya would land the ground safely Then you begin Day Warehouse is sub quest destination. You can go or not. But I suggest you should go. Here I write the strategy for Warehouse first okay?
This place is haunted. Check the first chest to get PPK Handgun. This gun is very annoying because it can shoot 5 bullets each time charging Active Time Battle. Then open the door to get to the house. The first chest here, you grab CM Protector. Going deeper, you are welcomed by a small Rat chased by a Cat. But the Rat becomes bigger into a Super Rat and it gets rid of the damn Cat. Of course, you must fight it. Remember to grab the Warehouse Key in the bottom right the sparkling thing.
Open the right chest to get M Grenade Launcher. Then go to the next door. Go along the room to the south area. Here there are some chests which one of them contains Rocket Launcher ammo. But now you don't have the weapon. Okay, get on the stairs to save and you can find a Weapon Plus here.
Then unlock the left door by the key and get through it. You are in a narrow path and two spiders might want to see you. Just get them all and go to the other side. This room has a lot of chests with useful items. Take them and equip if you can. Then climb down the rail into below floor. Go around that place. You'll be attacked by a Giant Crab One of the dangerous hit of the crabs is casting the water balls.
They are cast in multiple and there's no position to avoid except beside the crab. But first of all, check his attacks : - Strike : The crab may use this fatal attack with his arm when you stands too close to either side of him. That's the reason why you must kill the arm you are standind at as soon as possible. At this time of the game, if you have always fixed your guns with Tools, it would be strong enough to get rid of the arm after a few shots.
If you get two of the beams, you may lose more than HP. And that's not good. Haste is the best way to dodge these lasers. You just try to run to wherever you can. But if you haven't cast the spell yet, try to run to a large area where you can be free for a while. If you are not blocked by anything on your way, you may avoid the beams safely.
He casts several water balloons all over screen, and it's impossible to avoid if you are within. Two big hands of the crab swing out. And if you are too close to either hand, you'll get hit. Well, keep a pretty small distance okay?
Check the place around, until you find a Tool on the floor. But it is covered by some poison gas. Try to wait until the gas is off. Enter and get it as soon as possible if you really want to and then run out. Now you have nothing else to do there. So get to your next destination : Chinatown. In the second sight, you can find chest with M Grenade Launcher in the left side and a Save Point in the right side.
Now reach the last sight of this place. Maeda is here to check something. He suggests you to climb down the sewer. Before doing this, reach the two chests around the statue to grab some items.
Then descend the sewer. If you are here the first time, you would think it's a matrix. But it's not. You would find the order after some moments for exploring. Here let me chart a map for you to this place. Maybe my chart is clear enough for you to understand the order of this place?
Climb up the ladder to the upper corridor. Go right to grab Club 3. Then go south to see a FMV Maybe you still remember the tragedy in Central Park where a lot of innocent people were changed into elastic liquid. But how would EVE's predictions fare compared with findings made from actual clinical experiments, the gold standard of assessing how a genetic mutation affects physiologic function? To answer this question, the team compared EVE's scores against results from clinical experiments involving well-studied mutations in five genes, among them genes related to various forms of cancer, several cancer syndromes, and heart rhythm disorders.
EVE's predictions overlapped with current labels from experimental data. A notable advantage that EVE has over current methods is that it assigns a continuous score rather than a binary score.
This is because even when gene variants are labeled as benign or pathogenic, how a mutation might manifest physiologically is more nuanced. Does the mutation mean I am going to get pain in my little toe, or am I going to die tomorrow? Another important aspect of the tool is that it assigns a confidence-of-prediction score on a gene-by-gene basis. This can help clinicians contextualize the degree of certainty for any prediction. In other words, for each genetic variant, EVE tells the expert how much they can trust its call.
This is a matter of trustworthiness, of confidence in the model, the researchers said. The tool can say, 'I think that variant belongs to that pile, but I've never seen any variants like that before so take that with a grain of salt. This type of modeling is still in its infancy, and it's clear that evolution and genetic variation still have much to teach us about disease, the researchers said, adding that they plan to extend the work to other parts of the genome beyond protein-coding regions.
In the immediate future, however, the urgent task is to make clinical use of the genetic variation for which we do have some understanding. To do so, the researchers have already teamed up with a genome-sequencing company and are collaborating with various groups via the Chan Zuckerberg Initiative.
The team is also participating in the Atlas of Variant Effects Alliance, a global research effort whose mission is to map the effects of variation across the genome and create a comprehensive atlas of all possible human gene variants and their effects on protein function and physiology.
The ultimate goal of the effort is to improve the diagnosis, prognosis, and treatment of human disease. Materials provided by Harvard Medical School. Original written by Ekaterina Pesheva. Note: Content may be edited for style and length. Science News. Disease variant prediction with deep generative models of evolutionary data. Nature , ; DOI: ScienceDaily, 27 October Harvard Medical School. All about Eve, sophisticated AI: AI model called EVE shows remarkable capacity to interpret the meaning of gene variants in humans as benign or disease-causing.
Retrieved November 11, from www. The study identifies features associated with pathogenic and benign variants that However, different people are more susceptible to heart disease based on very slight differences in their genes, called Many people ScienceDaily shares links with sites in the TrendMD network and earns revenue from third-party advertisers, where indicated.
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